FAMAT Flexible Containment Chamber for Safe Powder Sampling

Introduction

Maintaining containment throughout powder handling operations is essential when processing highly potent pharmaceutical ingredients.

The FAMAT ZIP Sleeve System, developed with Flecotec ZIP technology, provides a flexible and reliable containment solution for transferring powders between process equipment while maintaining OEB 5 containment. Its unique ZIP connection ensures components can only be separated when correctly disengaged, reducing the risk of operator exposure and product contamination.

Watch the video below to discover how the ZIP Sleeve System simplifies contained powder handling.

What is the ZIP Sleeve System?

The ZIP Sleeve System is a flexible containment accessory designed to safely connect process equipment while maintaining a closed transfer path.

Manufactured from pharmaceutical-grade film compliant with FDA and EU regulations, the system integrates with FAMAT sampling valves using a dedicated canister. The patented ZIP mechanism allows transfer operations only when both ZIP components are correctly connected, ensuring safe handling of highly potent powders.

Key Features & Benefits

• Flexible OEB 5 containment solution
• Patented ZIP connection technology
• Pharmaceutical-grade FDA and EU compliant film
• Compatible with FAMAT sampling valves
• Prevents cross contamination
• Protects operators during powder transfer
• Static dissipative material suitable for Ex zones
• Modular connection to multiple process interfaces

How the ZIP Sleeve System Works

1. Connect the ZIP components

The two ZIP interfaces are securely coupled, creating a closed transfer path.

2. Perform the transfer

Powders are transferred while maintaining containment throughout the operation.

3. Disconnect safely

The ZIP mechanism can only be separated once the transfer is complete, helping prevent accidental powder release.

4. Continue production

The flexible system adapts easily to different process configurations.

Why Choose the ZIP Sleeve System?

The ZIP Sleeve System offers a versatile containment solution for pharmaceutical and API manufacturing.

Its modular design enables manufacturers to connect different equipment while maintaining operator protection and minimizing cross contamination throughout the production process.

Typical Applications

The ZIP Sleeve System is ideally suited for:

• HPAPI manufacturing
• Pharmaceutical production
• API processing
• Powder transfer
• Isolators
• Contained sampling
• Flexible containment interfaces

Engineering Insight

Containment is only as strong as the weakest connection in the process. By integrating proven ZIP connection technology with FAMAT sampling solutions, manufacturers can extend high-containment performance across multiple transfer operations while maintaining flexibility and ease of use.

FAQ

What is the ZIP Sleeve System?

The ZIP Sleeve System is a flexible containment solution that enables safe powder transfer between process equipment while maintaining a closed, high-containment environment.

Which containment level does it achieve?

The system is designed to comply with OEB 5 containment requirements when used as intended within a validated process.

Is it compatible with FAMAT sampling valves?

Yes. The ZIP Sleeve System interfaces directly with FAMAT sampling valves through a dedicated canister.

What are the advantages of ZIP technology?

The patented ZIP mechanism ensures components can only be connected and separated in the correct sequence, helping maintain containment throughout powder transfer operations.

Which industries use the ZIP Sleeve System?

The system is primarily used in pharmaceutical manufacturing, HPAPI production, biotechnology and other industries handling highly potent powders.

Related Videos

• 125TC/OEL High Containment Sampling System – Representative sampling under OEB 5 conditions.
• Continuous Liner System – Continuous contained powder transfer solution.
• Flexible Containment Chamber – Flexible OEB 4 containment accessory.
• 125S Safety Sampling Valve – Mechanical Poka-Yoke protection for safer sampling.

Related White Papers

• High-Containment Sampling for HPAPIs
• Cross Contamination in Industrial Sampling
• Representative Powder Sampling: Principles, Best Practices and Industrial Applications
• How to Select the Right Sampling Valve for Your Process

Related Application Notes

• HPAPI Sampling
• High Containment Powder Sampling
• Pharmaceutical Powder Sampling
• Sterile Sampling