Continuous Liner System to Achieve Powder Containment Sampling
Introduction
Handling highly potent powders requires safe and reliable containment throughout the production process. The FAMAT Continuous Liner System provides an effective solution for transferring powders under fully contained conditions while protecting operators, preserving product purity and preventing cross contamination.
Compatible with FAMAT sampling valves, the system integrates seamlessly into pharmaceutical and API manufacturing processes requiring OEB 5 containment performance.
Watch the video below to discover how the Continuous Liner System simplifies contained powder transfer.
What is the Continuous Liner System?
The Continuous Liner System is a high-containment accessory designed to safely transfer powders without breaking containment.
Manufactured from pharmaceutical-grade film compliant with FDA and EU regulations, it enables multiple bag filling operations while maintaining operator protection and product integrity. The patented ZIP connection technology ensures that transfer can only take place when both ZIP components are correctly connected.
Key Features & Benefits
- Continuous powder transfer under contained conditions
- OEB 5 containment performance (<1 μg/m³)
- Prevents cross contamination
- Pharmaceutical-grade FDA and EU compliant film
- Compatible with FAMAT sampling valves
- Suitable for Bag-In/Bag-Out applications
- Static dissipative material suitable for Ex zones
- Easy Tri-Clamp installation
How the Continuous Liner System Works
1. Connect the liner
The pharmaceutical-grade liner is securely connected to the FAMAT sampling system.
2. Transfer the product
Powder is transferred into the continuous liner while maintaining full containment.
3. Seal the filled section
The liner is sealed before separation, preventing product release.
4. Continue production
A new bag section is immediately available without breaking containment.
Why Choose the Continuous Liner System?
The Continuous Liner System offers a flexible containment solution for pharmaceutical manufacturers handling highly potent powders.
Its modular design minimizes operator exposure, simplifies bag changes and supports GMP-compliant manufacturing while maintaining excellent containment performance.
Typical Applications
The Continuous Liner System is commonly used for:
- HPAPI manufacturing
- Pharmaceutical production
- Powder transfer
- API processing
- Bag-In/Bag-Out systems
- Isolators
- Contained sampling operations
Engineering Insight
Maintaining containment during powder transfer is just as important as containment during sampling. By combining the Continuous Liner System with FAMAT sampling valves, manufacturers can extend containment throughout the sampling and product handling process while reducing operator exposure and contamination risks.
FAQ
What is a Continuous Liner System?
A Continuous Liner System allows powders to be transferred into multiple bags under contained conditions without breaking containment, protecting both operators and product quality.
Which containment level does the system achieve?
The system has been proven to provide containment levels below 1 μg/m³, making it suitable for OEB 5 applications.
Is the Continuous Liner compatible with FAMAT sampling valves?
Yes. It interfaces directly with FAMAT sampling valves through a dedicated canister, providing a fully integrated containment solution.
Can it be used for Bag-In/Bag-Out operations?
Yes. The system is suitable for Bag-In/Bag-Out applications involving powders, tablets, vials, tools and waste handling.
Which industries use Continuous Liner Systems?
Continuous Liner Systems are widely used in pharmaceutical manufacturing, API production, biotechnology and other industries handling highly potent powders.
Related Videos
- 125TC/OEL High Containment Sampling System – OEB 5 contained powder sampling.
- Flexible Containment Chamber – Flexible OEB 4 containment solution for powder sampling.
- ZIP Sleeve System – Flexible contained transfer using ZIP technology.
- 125S Safety Sampling Valve – Mechanical Poka-Yoke system for safer sampling operations.
Related White Papers
- High-Containment Sampling for HPAPIs
- Cross Contamination in Industrial Sampling
- Representative Powder Sampling: Principles, Best Practices and Industrial Applications
- How to Select the Right Sampling Valve for Your Process
Related Application Notes
- HPAPI Sampling
- High Containment Powder Sampling
- Pharmaceutical Powder Sampling
- Sterile Sampling
